Skip to content
Marlbridge

AP® Biology · Unit 2 · Topic 2.2

Cell Size: Revision Notes (Biology 2.2)

One-page recap of surface area-to-volume ratio: the formulas, how the ratio changes with size and shape, membrane folds, heat exchange and metabolic rate per unit mass.

Short on time? This page is the recap. For explanations, figures and worked examples, use the full study guide.

Recap

  • Everything a cell takes in or gets rid of, including heat, crosses its surface. Every part of its volume creates demand.
  • As a cell grows, volume rises faster than surface area, so SA/V falls and demand per unit of surface rises. This limits cell size and shape.
  • Smaller cells have a higher SA/V and exchange materials more efficiently.
  • Flat or long shapes raise SA/V compared with a sphere of the same volume.
  • Membrane folds and projections add area for almost no volume: microvilli (gut lining), root hairs, cristae; leaves exchange gases through stomata controlled by guard cells.
  • Larger organisms have a lower SA/V, so they exchange heat more slowly per unit mass. Smaller organisms usually have a higher metabolic rate per unit body mass.

Key relationships

Shape SA V SA/V
Cube 6s² s³ 6/s
Sphere 4πr² (4/3)πr³ 3/r
Rectangular solid 2lh + 2lw + 2wh lwh calculate
Cylinder 2πrh + 2πr² πr²h calculate
Change Effect
length × k SA × k², V × k³, SA/V ÷ k
supply = SA × (uptake per unit area) demand = V × (use per unit volume)
supply = demand SA/V = demand rate ÷ supply rate

Assumptions behind the numbers

  • Cells are modelled as simple shapes; real cells are irregular.
  • Supply-and-demand models assume uptake is the same everywhere on the membrane and ignore distances inside the cell.
  • SA/V has units (µm⁻¹ when lengths are in µm); only compare ratios in the same units.

Mistakes to avoid

  1. Saying a larger cell has less surface area (it has less per unit volume).
  2. Leaving out the two ends of a cylinder (2πr²).
  3. Using diameter in place of radius.
  4. Dropping the units of SA/V.
  5. Thinking microvilli help by enlarging the cell rather than adding surface.
  6. Reversing the metabolic-rate trend: small organisms have the higher rate per unit mass.

Quick self-check

  1. SA/V of a cube of side 5 µm? (6 ÷ 5 = 1.2 µm⁻¹)
  2. SA/V of a sphere of radius 6 µm? (3 ÷ 6 = 0.5 µm⁻¹)
  3. Why does a mouse need more food per gram of body than a horse? (Its higher SA/V means it loses heat faster per gram, so it needs a higher metabolic rate per unit mass to stay warm.)

Next: practice questions.

AP® and Advanced Placement® are trademarks registered by the College Board, which is not affiliated with, and does not endorse, this website. Marlbridge is an independent tuition provider. It is not an authorized AP course provider, an AP school or an exam centre, and these resources are not official College Board materials. Reading them or doing simulations does not meet the laboratory requirement of an AP science course.