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AP® Biology · Unit 3 · Topic 3.5

Cellular Respiration: Topic Checklist (Biology 3.5)

Specific “I can…” statements for cellular respiration, each linked to the guide section and practice question that shows whether you can really do it.

Work through the list without notes. If you cannot do a statement, follow its link, then come back. Guide = study guide; Practice = practice questions.

Understanding

  • I can explain why respiration and fermentation are found in all forms of life, and what respiration is for. (Guide: “Why cells respire”)
  • I can define oxidation and reduction and explain the role of NAD⁺/NADH and FAD/FADH₂ as electron carriers. (Guide: “Oxidation, reduction and electron carriers”)
  • I can state where glycolysis, pyruvate oxidation, the Krebs cycle and the ETC happen, with the main inputs and outputs of each. (Guide: Figure 1; Practice Q1)
  • I can explain how electron transport builds a proton gradient across the inner mitochondrial membrane, and say which side has the higher pH. (Guide: Figure 2; Practice Q3)
  • I can explain how ATP synthase uses the proton gradient to make ATP, and why cristae increase ATP output. (Guide: “Stage 4”; Practice Q3)
  • I can describe how prokaryotes carry out chemiosmosis across the plasma membrane, and how anaerobic prokaryotes use acceptors other than oxygen. (Guide: “Stage 4”; Practice Q5)
  • I can explain how fermentation regenerates NAD⁺ so glycolysis continues without oxygen, and name its products. (Guide: “Fermentation”; Practice Q2)

Calculation and skills

  • I can construct a correctly labelled graph of respiration data, choosing the graph type and showing variability. (Guide: Worked example 1; Practice Q4)
  • I can calculate a rate of respiration per gram per hour from a graph or table. (Guide: Worked example 1)
  • I can convert a pH difference into a ratio of H⁺ concentrations. (Practice Q5)
  • I can compare the energy yield of aerobic respiration and fermentation using given model values. (Guide: Worked example 2; Practice Q7)

Reasoning

  • I can predict, link by link, the effects of blocking the ETC, blocking ATP synthase or letting protons leak across the membrane. (Guide: Worked example 2; Practice Q3, Q6)
  • I can explain how uncoupling in brown fat produces heat for an endotherm. (Guide: “Uncoupling”; Practice Q6)
  • I can compare the ETC and chemiosmosis in respiration and photosynthesis. (Guide: “Respiration and photosynthesis compared”)

All ticked? Move on to Topic 4.1, Cell Communication, or return to the course roadmap.

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