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AP® Biology · Unit 5 · Topic 5.4

Non-Mendelian Genetics: Topic Checklist (Biology 5.4)

Specific “I can…” statements for linkage and mapping, sex-linked traits, incomplete dominance, codominance, pleiotropy and organelle inheritance, each linked to a guide section or question.

Work through the list without notes. If you cannot do a statement, follow its link, then come back. Guide = study guide; Practice = practice questions.

Understanding

  • I can distinguish incomplete dominance from codominance, with an example of each. (Guide: “Incomplete dominance and codominance”; Practice Q7)
  • I can explain why linked genes do not assort independently, and how crossing over produces recombinants. (Guide: “Linked genes and gene mapping”; Practice Q5)
  • I can explain why X-linked recessive traits are more common in XY individuals, and why an affected father cannot pass one to his son. (Guide: “Sex-linked traits”; Practice Q2)
  • I can describe ZW sex determination in birds and haplodiploidy in bees, and predict which sex shows a Z-linked recessive trait more often. (Guide: “Other sex-determination systems”; Practice Q6)
  • I can explain pleiotropy and tell it apart from linkage using cross data. (Guide: “Pleiotropy”; Practice Q1, Q7)
  • I can explain why mitochondrial and chloroplast traits are typically inherited from the mother and do not follow Mendel’s ratios. (Guide: “Non-nuclear inheritance”; Practice Q3)

Calculation and skills

  • I can calculate recombination frequency from test-cross data and convert it to map units. (Guide: Worked example 2; Practice Q5)
  • I can order three genes from their pairwise map distances. (Guide: Figure 1; Practice Q4)
  • I can use a Punnett square to predict sons and daughters in an X-linked or Z-linked cross. (Guide: Figure 2, Worked example 3; Practice Q2, Q6)
  • I can use chi-square to test a 1 : 2 : 1 or 1 : 1 : 1 : 1 hypothesis and state the conclusion correctly. (Guide: Worked examples 1 and 2; Practice Q5, Q7)

Reasoning

  • I can name the non-Mendelian pattern that best explains a data set, and support it with a specific clue. (Guide: “When the ratios do not fit”; Practice Q1, Q3)
  • I can use reciprocal crosses to tell organelle inheritance from nuclear inheritance. (Guide: “Non-nuclear inheritance”; Practice Q3)
  • I can predict how changing the arrangement of alleles in a parent changes which classes are parental, and explain why map distance stays the same. (Practice Q5)

All ticked? Move on to Topic 5.5, Environmental Effects on Phenotype, or return to the course roadmap.

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