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AP® Biology · Unit 7 · Topic 7.5

Hardy–Weinberg Equilibrium: Topic Checklist (Biology 7.5)

Specific “I can…” statements for the Hardy–Weinberg model, each linked to the guide section and practice question that shows whether you can really do it.

Work through the list without notes. If you cannot do a statement, follow its link, then come back. Guide = study guide; Practice = practice questions.

Understanding

  • I can explain what Hardy–Weinberg equilibrium describes and why it represents a population that is not evolving. (Guide: “A model of a population that is not changing”)
  • I can list the five conditions and name the evolutionary force each one rules out. (Guide: “The five conditions”; Practice Q2)
  • I can explain why the conditions are never all met, and why the model is still useful as a null hypothesis. (Guide: “The five conditions”)
  • I can explain where p², 2pq and q² come from using random union of gametes. (Guide: Figure 1)
  • I can explain why inbreeding or self-fertilisation changes genotype frequencies but not, by itself, allele frequencies. (Guide: “The five conditions”; Practice Q6)

Calculation and skills

  • I can calculate p and q by counting alleles from genotype numbers. (Guide: Worked example 1; Practice Q3, Q6)
  • I can find q from the frequency of a recessive phenotype, and then p, the carrier frequency and expected numbers. (Guide: Worked example 2; Practice Q1, Q7)
  • I can calculate expected genotype numbers and run a chi-square test with the correct degrees of freedom. (Guide: Worked example 3; Practice Q5)
  • I can describe a graph of allele frequency over generations using specific values. (Guide: “Graphs of allele frequency over time”; Practice Q4)

Reasoning

  • I can decide which condition is most likely broken from a description or a graph, and justify the choice. (Practice Q2, Q4)
  • I can state a correct conclusion after a chi-square test, saying “suggests” rather than “proves”. (Guide: Worked example 3; Practice Q5)
  • I can explain why selection removes a rare recessive allele slowly. (Guide: Worked example 2; Practice Q7)
  • I can explain when √(q²) gives a misleading answer. (Guide: “Two routes to allele frequencies”; Practice Q7)

All ticked? Move on to Topic 7.6, Evidence of Evolution, or return to the course roadmap.

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